Last Week’s Hot Topic on Endometriosis


Last week’s hot topic on endometriosis was Endometriosis Study Could Shed Light on Cause of Condition, Help Lead to Treatments written by Alisa Woods.

This article focused on a new study from Wuhan, China, and may help uncover the causes of endometriosis. According to the report, a specific cellular pathway called the Wnt/β-catenin pathway could induce matrix metalloproteinase 9 (MMP-9) expression, which in turn may cause endometriosis. MMP-9 is a type of enzyme involved in several different biological functions. The paper, “Intracellular Wnt/beta-catenin signaling underlying 17beta-estradiol-induced matrix metalloproteinase 9 expression in human endometriosis,“ appeared in the journal Biology of Reproduction.

The study sheds light on a possible cause of endometriosis and could lay the groundwork for potential new treatments for endometriosis that specifically target β- catenin and MMP-9.

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