biomarker

January 17, 2019January 17, 2019

Reduced Levels of HOXA10 Gene Linked to Infertility, Endometriosis Severity, Study Suggests

News

Reduced HOXA10 gene expression (protein production) levels in the endometrial tissue may be linked to endometriosis severity and infertility, a study suggests. Researchers, supported by these findings, believe HOXA10 gene activity ... Read more

January 8, 2019January 8, 2019

Active GATA6 Gene May Be Biomarker for Endometriosis Lesions, Early Study Suggests

News

Activation of a gene called GATA6 may be a useful biomarker to aid in the diagnosis of endometriosis lesions, an early research study reports. The study provides evidence that endometriotic cells ... Read more

December 21, 2016December 21, 2016

Specific Proteins and Their Inhibitors May Be Therapeutic Targets for Endometriosis

News

Several studies have demonstrated that specific proteins called matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) are key elements in the remodeling process that occurs in the inner uterus ... Read more

September 21, 2016

Database Collaboration Aims to Create Better Diagnostics and Understanding of Endometriosis

News

In an effort to overcome the current holes in clinical data regarding cause, pathogenesis and progression of the endometriosis (EM), a group of European researchers have decided to use data-mining ... Read more

March 11, 2016March 11, 2016

Endometriosis May Be Detected in Its Early Stages Through Serum Levels of a Protein

News

Serum levels of tumor necrosis factor-alpha (TNF-a) are elevated in endometriosis patients, particularly in early stages of the disease, and may serve as a diagnostic biomarker, according to a study titled “Soluble ... Read more

December 16, 2015December 16, 2015

Natural Gene Variants May Protect Against Endometriosis

News

In a new study entitled “Evaluation of Tumor Necrosis Factor Alpha Polymorphism Frequencies in Endometriosis,” researchers investigated how natural variants (polymorphisms) within the promoter region of the tumor necrosis factor-alpha ... Read more